multiple congenital anomalies syndrome

What You Need to Know About Malan Syndrome in Children

What You Need to Know About Malan Syndrome in Children

Malan syndrome is a multiple congenital anomalies syndrome. It is a rare genetic disorder that occurs because of change in the NFIX gene (nuclear factor I/X (CCAAT-binding transcription factor)) located on the short arm ("p" arm) of chromosome 19 at position 13.2. Its prevalence is less than 1 per million.  What is Malan Syndrome? Malan syndrome is a genetic, non-life threatening disorder caused by a mutation in chromosome 19. Some Clinical features of Malan syndrome: tall staturestereotypical craniofacial features, such as tall forehead, long or triangular face, deeply set eyes, down-slanting eyes, low set ears, a small mouth that is…
Read More